Articles

VideoCardiovascularSauna

The Science of Heat Exposure: What Every Body Knows About Temperature

Deliberate heat exposure isn't about endurance. It's about activation. When you understand the mechanisms—how your body...
16 February 2026
VideoSaunaCardiovascular

The Science of Sauna: How Heat Builds Resilience

Dr. Rhonda Patrick and MedCram's Dr. Kyle Allred unpack the science behind sauna use—covering cardiovascular health, bra...
16 February 2026
PaperSaunaCardiovascular

The Impact of Sauna Bathing on Cardiovascular Homeostasis From Molecular

Filip Matusiak, Klaudia Brzoza1 January 2026
PaperCardiovascularWeight Loss

Blunted cardiovascular responses in individuals with type 2 diabetes and hypertension during cold and heat exposure

Mojdeh Rafieian, Erlend Hoftun Farbu, Anje Christina Höper, Rasmus Valtonen, Henna Hyrkäs-Palmu, Juha Perkiömäki, Craig Crandall, Jouni J. K. Jaakkola, Tiina Maria Ikäheimo1 January 2025
PaperBrown FatWeight Loss

Brown adipose tissue secretes OLFM4 to coordinate sensory and sympathetic innervation via Schwann cells

Mingqiang Lai, Wu Zhou, Wenchong Zou, Lianlian Qiu, Zhaoyu Liang, Wanyi Chen, Yiqing Wang, Bin Guo, Chaoran Zhao, Sheng Zhang, Pinglin Lai, Le Hu, Xiaolin Liu, Yu Jiang, Yinghua Chen, Min-jun Huang, Xiaochun Bai, Zhipeng Zou1 January 2025
PaperCardiovascularMetabolism

Cold environment regulates ischemic stroke through modulation of gut

Xiao Zhou, Chanjuan Wei, Jiaming Liu, Xiaoshuang Xia, Lin Wang, Xin Li1 January 2025
PaperRecoveryCryotherapy

Consensus on the Use of Therapeutic Interventions in Pain Management

Bailey McLagan, Kyle Silvey, Timothy Roberts, David Erceg, Jonathan C. Sum, E. Todd Schroeder1 January 2025
PaperRecoveryAthletic Performance

Differences in the Effectiveness of Different Physical Therapy

Jing Chen, Qing Hu, Jiajie Hu, Songtao Liu, Linyu Yin1 January 2025
PaperRecoveryContrast Protocol

Effects of thermal interventions on skeletal muscle adaptations and regeneration: perspectives on epigenetics: a narrative review

Tom Normand‑Gravier, Robert Solsona, Valentin Dablainville, Sébastien Racinais, Fabio Borrani, Henri Bernardi, Anthony M. J. Sanchez1 January 2025
PaperCardiovascularSauna

Acute Finnish sauna heating and cold water immersion effects on cardiovascular dynamic response in normotensive women

Rafał Szafraniec, Rafał Poręba, Jarosław Domaradzki1 January 2025
PaperBrown FatMetabolism

Acute cold exposure in humans shifts the circulating proteome to a cardioprotective and anti-aging profile

Kaja Plucińska, Zsu-Zsu Chen, Ruijie Xiang, Samir Zaman, Lu Yan, Charlotte Hurson, Christian Peterson, Katie Fredrickson, Laurie Farrell, Jeanne Walker, Meltem Ece Kars, Gaurav Tiwari, Olivier Pourquie, Yuval Itan, Thomas S. Carroll, Kong Y. Chen, Aaron M. Cypess, Robert E. Gerszten, Paul Cohen1 January 2025